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April 14, 2015: Last of 6 free REACH seminars with contributions of EURL ECVAM scientists: "(Zebra)Fish Embryo Acute Toxicity Test to predict short term toxicity to fish (and beyond)" Read more...
Updated information on alternative methods and testing strategies that could be used to meet REACH requirements

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Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testingdefault frame updated video

Transcripts: pdf icon EN; FR; DE; IT.

The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP) located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP). As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

Meeting of European 3Rs Centres 21-22 April 2015 Meeting of European 3Rs Centres 21-22 April 2015 - Apr 27, 2015 EURL ECVAM hosts first meeting of European 3Rs Centres (21-22 April 2015)
New reports published in the QSAR Model Database New reports published in the QSAR Model Database - Apr 10, 2015 Ten new reports have been published in the JRC QSAR Model Database that uses an internationally recognised format to provide key information on models which are all peer-reviewed before publication.
Reducing animal testing for skin allergies Reducing animal testing for skin allergies - Mar 02, 2015 The JRC has validated and recommended a new method, not based on animal testing, which identifies chemicals that can trigger skin allergies, estimated to affect already 20% of the population in Europe.
Breakthrough towards animal-free testing for chemicals that might cause skin allergies Breakthrough towards animal-free testing for chemicals that might cause skin allergies - Feb 05, 2015 Today's adoption by the OECD of two new test guidelines will contribute to reducing the number of animals currently used worldwide to identify chemicals with the potential to trigger skin allergies.
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calls

Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
Call for expressions of interest - EURL ECVAM Stakeholder forum (ESTAF) Open Invitation addressed to stakeholder organisations
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multimedia

New EURL ECVAM video explains the validation process of alternative methods (in Italian) New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods