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Review of the Availability of In Vitro and In Silico Methods for Assessing Dermal Bioavailability Read more...

 

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Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testingdefault frame updated video

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The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP) located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP). As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

EU and Brazil strengthen international cooperation on alternatives to animal testing EU and Brazil strengthen international cooperation on alternatives to animal testing - May 04, 2016 European experts in alternative approaches to animal testing promote current and future collaborations with partners in Brazil
Regulators adopt mechanistically-based non-animal test methods to assess the potential of chemicals to cause skin allergy Regulators adopt mechanistically-based non-animal test methods to assess the potential of chemicals to cause skin allergy - Apr 26, 2016 EURL ECVAM validated methods adopted by the OECD paved the way for the revision of regulatory requirements for skin sensitisation under REACH
EU-NETVAL welcomes new member facilities EU-NETVAL welcomes new member facilities - Mar 17, 2016 The European Union Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) was set up by EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) in response to the provision of Directive 2010/63/EU on the protection of animals used for scientific purposes which requests that EU Member States assist the European Commission in the validation of alternative methods
Predicting chemicals that may cause skin allergy - validated non-animal methods do not miss chemicals requiring activation Predicting chemicals that may cause skin allergy - validated non-animal methods do not miss chemicals requiring activation - Mar 01, 2016 In order to inform ongoing discussions at the regulatory level in the EU, the JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), supported by a group of experts, analysed the extent to which validated non-animal methods are able to correctly identify chemicals that need to be activated to acquire skin sensitisation potential.
Alternatives to animal testing - EU Public survey launched Alternatives to animal testing - EU Public survey launched - Feb 01, 2016 Accelerating progress in the Replacement, Reduction and Refinement of animal testing through better knowledge sharing
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calls

EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) Supporting the validation and implementation of in vitro methods for regulatory use
Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
Call for expressions of interest - EURL ECVAM Stakeholder forum (ESTAF) Open Invitation addressed to stakeholder organisations
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multimedia

Toxicological Testing of Chemicals & EURL ECVAM Toxicological Testing of Chemicals & EURL ECVAM Faces of Science - showcasing the human face of the scientific advice supporting EU policy. Maurice Whelan at the Joint Research Centre, the European Commission's in-house science service, presents the Toxicological Testing of Chemicals and EURL ECVAM
New EURL ECVAM video explains the validation process of alternative methods (in Italian) New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods