EURL ECVAM Latest News

Improving ways of predicting the bioconcentration of environmental chemicals in fish

Improving ways of predicting the bioconcentration of environmental chemicals in fish

JRC scientists have contributed to two new OECD Test Guidelines that describe how to measure in vitro fish hepatic clearance. This information is key for making more reliable predictions of bioconcentration of chemicals in fish when combined with mathematical models.

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International guidance on good practice for the development and application of in vitro methods

International guidance on good practice for the development and application of in vitro methods

The Organisation for Economic Cooperation and Development (OECD) has published guidance on Good In Vitro Method Practices (GIVIMP) to ensure the reliability and integrity of in vitro data used for the safety assessment of chemicals. JRC scientists of the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) contributed to the guidance, within the context of a project of the OECD Test Guidelines Programme.

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Improving chemical testing approaches for developmental neurotoxicity assessment

Improving chemical testing approaches for developmental neurotoxicity assessment

JRC scientists – in close collaboration with experts from international organisations - develop, evaluate and promote non-animal testing strategies based on in vitro methods to improve the regulatory assessment of chemicals which may cause developmental neurotoxicity (DNT) effects.

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Calls for tender seek experts for training tools on alternatives to animal testing

Calls for tender seek experts for training tools on alternatives to animal testing

The European Commission has recently launched open calls for tender inviting experts to develop eLearning tools to facilitate uptake of non-animal alternative approaches in science.

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JRC launches survey on alternatives to animal testing

JRC launches survey on alternatives to animal testing

The JRC launches a survey today as part of a major study aimed at providing an overview of education and training opportunities which are relevant to Replacing, Reducing or Refining the use of animals for scientific purposes – known as the '3Rs'.

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EURL ECVAM renews its Scientific Advisory Committee

EURL ECVAM renews its Scientific Advisory Committee

New ESAC will meet in December to review affinity reagents produced using animal-free technologies and methods for skin sensitisation.

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Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing

Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing

The JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a survey to collect scientific opinion on how to assess the relevance and fitness-for-purpose of complex in vitro models such as organ-on-chip devices to understand how to best facilitate their uptake and application in a variety of areas including biomedical research for drug development and toxicological testing for safety assessment.

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Optimising validation studies of non-animal methods for vaccine testing

Optimising validation studies of non-animal methods for vaccine testing

New report summaries the outcome of a workshop organised by the Joint Research Centre's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) and VAC2VAC* partners on the design of multi-centre validation studies.

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Reviewing the use of alternative methods in biomedical research

Reviewing the use of alternative methods in biomedical research

The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a study to review alternative methods and models being used for research in the areas of Respiratory Tract Diseases and Neurodegenerative Disorders.

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