EURL ECVAM Latest News

JRC launches survey on alternatives to animal testing

JRC launches survey on alternatives to animal testing

The JRC launches a survey today as part of a major study aimed at providing an overview of education and training opportunities which are relevant to Replacing, Reducing or Refining the use of animals for scientific purposes – known as the '3Rs'.

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EURL ECVAM renews its Scientific Advisory Committee

EURL ECVAM renews its Scientific Advisory Committee

New ESAC will meet in December to review affinity reagents produced using animal-free technologies and methods for skin sensitisation.

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Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing

Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing

The JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a survey to collect scientific opinion on how to assess the relevance and fitness-for-purpose of complex in vitro models such as organ-on-chip devices to understand how to best facilitate their uptake and application in a variety of areas including biomedical research for drug development and toxicological testing for safety assessment.

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Optimising validation studies of non-animal methods for vaccine testing

Optimising validation studies of non-animal methods for vaccine testing

New report summaries the outcome of a workshop organised by the Joint Research Centre's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) and VAC2VAC* partners on the design of multi-centre validation studies.

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Reviewing the use of alternative methods in biomedical research

Reviewing the use of alternative methods in biomedical research

The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a study to review alternative methods and models being used for research in the areas of Respiratory Tract Diseases and Neurodegenerative Disorders.

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Mapping education and training on the 3Rs

Mapping education and training on the 3Rs

The JRC has launched a study to review available education and training resources that support the 3Rs approach: Replacement, Reduction and Refinement of animal procedures used for scientific purposes.

Mapping education and training on the 3Rs - Read More…

JRC portal ChemAgora simplifies access to chemical data

JRC portal ChemAgora simplifies access to chemical data

The JRC's ChemAgora web portal provides search capabilities to retrieve chemical data from a plethora of online resources enabling users to access both regulatory information on chemicals and public databases on chemical properties.

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How to assess the safety of nanomaterials with less animal testing?

How to assess the safety of nanomaterials with less animal testing?

The JRC participated in an expert group of regulators, academics and industry to discuss the way forward in nanotoxicology, concluding that there is a strong potential for use of alternative methods that will impact the reduction, refinement and replacement (3Rs) of animal testing.

How to assess the safety of nanomaterials with less animal testing? - Read More…

Good progress in carcinogenicity assessment of chemicals

Good progress in carcinogenicity assessment of chemicals

The outcome of a workshop reviewing progress in carcinogenicity assessment of chemicals has been published in the latest issue of Toxicology in Vitro Special Issue. The workshop was organised by the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and the European Society of Toxicology In Vitro (ESTIV) and identified opportunities for exploiting recent advances in test methods and assessment approaches to move away from the two-year cancer bioassay in rodents.

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Adapting the Adverse Outcome Pathway concept to biomedical research

Adapting the Adverse Outcome Pathway concept to biomedical research

JRC scientists have explored the application of Adverse Outcome Pathways (AOP) to improve mechanistic understanding of human disease pathophysiology in order to advance biomedical research and inform the development of new drugs.

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