EURL ECVAM Latest News

JRC hosts a meeting to strengthen its collaboration with the European Food Safety Authority (EFSA)

JRC hosts a meeting to strengthen its collaboration with the European Food Safety Authority (EFSA)

On 5th April JRC-Ispra hosted a delegation from EFSA to discuss specific topics of common interest in the area of risk assessment related to chemicals.

JRC hosts a meeting to strengthen its collaboration with the European Food Safety Authority (EFSA) - Read More…

Understanding nanomaterial toxicity by leveraging mechanistic information on chemicals

Understanding nanomaterial toxicity by leveraging mechanistic information on chemicals

JRC scientists carried out a study illustrating how the mechanisms of nanomaterial toxicity can be better understood by exploiting the broader body of mechanistic information on chemicals in general.

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The pathway from liver injury to liver fibrosis

The pathway from liver injury to liver fibrosis

JRC scientists have used an Adverse Outcome Pathway approach to explain how some chemicals can potentially cause liver fibrosis in humans in order to support the development of non-animal approaches to chemical safety assessment.

The pathway from liver injury to liver fibrosis - Read More…

EURL ECVAM is inviting public comments on its draft Recommendation on the use of non-animal approaches for skin sensitisation testing

The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is inviting public comments on its latest draft Recommendation concerning the use of non-animal approaches for skin sensitisation testing.

EURL ECVAM is inviting public comments on its draft Recommendation on the use of non-animal approaches for skin sensitisation testing - Read More…

JRC meets with OECD experts to define good practices for in vitro methods

JRC meets with OECD experts to define good practices for in vitro methods

On the 23rd and 24th of March the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) hosted a meeting with OECD experts to discuss the draft of a guidance document on Good In Vitro Method Practice (GIVIMP). This GIVIMP document would serve as a technical guidance on good scientific and quality practices to support the regulatory human safety assessment of chemicals using in vitro methods.

JRC meets with OECD experts to define good practices for in vitro methods - Read More…

JRC supports the use of stem cells for non-animal approaches to regulatory toxicity assessment

JRC supports the use of stem cells for non-animal approaches to regulatory toxicity assessment

New publication summarises the outcome of a workshop organised by the European Partnership of Alternatives to Animal Testing (EPAA) on the use of stem cell-derived in vitro test systems in toxicology.

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Reducing animal testing through better knowledge sharing

Reducing animal testing through better knowledge sharing

The JRC has carried out a study of available knowledge on the replacement, reduction and refinement (the 3Rs) of animal procedures used in research and testing to understand how supply of such knowledge can better meet demand. Findings show that although much 3Rs knowledge exists, its sharing can be improved through better coordination, communication and outreach, and by more emphasis on targeted education and training initiatives.

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A 21st-century roadmap for biomedical research

A 21st-century roadmap for biomedical research

JRC scientist contributes to the definition of a 21st-century roadmap for biomedical research which proposes the use of human-specific models and innovative in vitro technologies instead of animals.

A 21st-century roadmap for biomedical research - Read More…

JRC hosts the VAC2VAC workshop on validation of non-animal methods for quality control of vaccines

JRC hosts the VAC2VAC workshop on validation of non-animal methods for quality control of vaccines

The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) organised this workshop with VAC2VAC partners from the 30th January to the 1st February 2017 to discuss ways of improving multi-centre validation studies and making use of the data generated for product-specific validation purposes.

JRC hosts the VAC2VAC workshop on validation of non-animal methods for quality control of vaccines - Read More…

How Adverse Outcome Pathways can support computational approaches to predictive toxicology

How Adverse Outcome Pathways can support computational approaches to predictive toxicology

Scientists from the JRC and eleven collaborating organisations from the EU, Canada and the USA have shared their collective insights on how adverse outcome pathways (AOP) can aid the development and use of computational prediction models for regulatory toxicology.

How Adverse Outcome Pathways can support computational approaches to predictive toxicology - Read More…

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