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New publication summarises the outcome of a workshop organised by the European Partnership of Alternatives to Animal Testing (EPAA) on the use of stem cell-derived in vitro test systems in toxicology.
The JRC has carried out a study of available knowledge on the replacement, reduction and refinement (the 3Rs) of animal procedures used in research and testing to understand how supply of such knowledge can better meet demand. Findings show that although much 3Rs knowledge exists, its sharing can be improved through better coordination, communication and outreach, and by more emphasis on targeted education and training initiatives.
JRC scientist contributes to the definition of a 21st-century roadmap for biomedical research which proposes the use of human-specific models and innovative in vitro technologies instead of animals.
The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) organised this workshop with VAC2VAC partners from the 30th January to the 1st February 2017 to discuss ways of improving multi-centre validation studies and making use of the data generated for product-specific validation purposes.
Scientists from the JRC and eleven collaborating organisations from the EU, Canada and the USA have shared their collective insights on how adverse outcome pathways (AOP) can aid the development and use of computational prediction models for regulatory toxicology.
JRC scientists - in close collaboration with international organisations – revised the first guidance on Good Cell Culture Practice (GCCP) by expanding it to aspects of quality assurance for in vitro cell culture focusing on the increasingly diverse cell types and culture formats used in research and elsewhere.
Criteria for selection of reference chemicals for the evaluation of alternative methods to assess developmental neurotoxicity
In collaboration with international organisations, a JRC scientist defined criteria for the selection of positive/negative control samples to assess developmental neurotoxicity hazard posed by environmental and industrial chemicals.
The Joint Research Centre's EU Reference Laboratory for Alternative to Animal Testing (EURL ECVAM) has entirely revamped its Tracking System for Alternative methods towards Regulatory acceptance (TSAR), recently launched at the Commission’s scientific conference on “Non-animal Approaches-The way Forward” held on 6-7 December in Brussels.
JRC Summer School on Alternative Approaches for Risk assessment - THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT
The JRC's Chemical Safety and Alternative Methods Unit, which incorporates the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), is organising a JRC Summer School from the 16-19 May 2017, at the JRC Ispra site, on the topic of "Alternative Approaches for Risk Assessment". The overall aim is to provide comprehensive training on state-of-the-art alternative (non-animal) approaches to predictive toxicology and to promote their use within modern chemical risk assessment practice.
The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is renewing membership of its EURL ECVAM Scientific Advisory Committee (ESAC). Interested scientific experts who satisfy the eligibility criteria and who possess the relevant competences are invited to apply (Deadline 31st January 2017).