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SEURAT-1 Workshop: The read-across case study for safety assessment contributing to the SEURAT-1 Proof of Concept

Event details
Apr 29, 2014 09:00 AM to
Apr 30, 2014 01:00 PM
Ispra (Varese, Italy)
Organizer: SEURAT-1

The meeting is restricted to invited participants

On 29 and 30 April 2014, the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre will organise a SEURAT-1 Workshop in its premises, in Ispra (Varese, Italy).

EURL ECVAM supports the activities of the SEURAT-1 Safety Assessment Working Group and contributes to the ultimate Proof-of-Concept of the SEURAT-1 research initiative, i.e. to demonstrate that safety assessment of chemicals for repeated dose toxicity can be made by an improved read across from data rich to data poor substances not only based on structural relation but by additional evidence from alternative methods.

SEURAT-1 is a 5 year Research Initiative started in 2011 aiming on the replacement of repeated dose systemic toxicity testing in vivo, used for the assessment of human safety (Safety Evaluation Ultimately Replacing Animal Testing). The overall goal is the development of in vitro and in silico test systems based on mechanistic understanding of toxicological effects caused through repeated exposure, which can ultimately support regulatory safety assessment. Seurat-1 has a 50 million Euro funding jointly available from the European Union’s Health Programme and the European Cosmetics Industry aiming on making animal testing obsolete.

Recent achievements by SEURAT-1 have been illustrated at its recent Annual meeting in Barcelona (5-6 February 2014).

For more information, see SEURAT-1 web site.