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Optimising validation studies of non-animal methods for vaccine testing - May 03, 2018
Optimising validation studies of non-animal methods for vaccine testing
New report summaries the outcome of a workshop organised by the Joint Research Centre's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) and VAC2VAC* partners on the design of multi-centre validation studies.
Reviewing the use of alternative methods in biomedical research - Apr 19, 2018
Reviewing the use of alternative methods in biomedical research
The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a study to review alternative methods and models being used for research in the areas of Respiratory Tract Diseases and Neurodegenerative Disorders.
Mapping education and training on the 3Rs - Feb 27, 2018
Mapping education and training on the 3Rs
The JRC has launched a study to review available education and training resources that support the 3Rs approach: Replacement, Reduction and Refinement of animal procedures used for scientific purposes.
JRC portal ChemAgora simplifies access to chemical data - Feb 09, 2018
JRC portal ChemAgora simplifies access to chemical data
The JRC's ChemAgora web portal provides search capabilities to retrieve chemical data from a plethora of online resources enabling users to access both regulatory information on chemicals and public databases on chemical properties.
How to assess the safety of nanomaterials with less animal testing? - Feb 05, 2018
How to assess the safety of nanomaterials with less animal testing?
The JRC participated in an expert group of regulators, academics and industry to discuss the way forward in nanotoxicology, concluding that there is a strong potential for use of alternative methods that will impact the reduction, refinement and replacement (3Rs) of animal testing.
Good progress in carcinogenicity assessment of chemicals - Jan 17, 2018
Good progress in carcinogenicity assessment of chemicals
The outcome of a workshop reviewing progress in carcinogenicity assessment of chemicals has been published in the latest issue of Toxicology in Vitro Special Issue. The workshop was organised by the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and the European Society of Toxicology In Vitro (ESTIV) and identified opportunities for exploiting recent advances in test methods and assessment approaches to move away from the two-year cancer bioassay in rodents.
Adapting the Adverse Outcome Pathway concept to biomedical research - Jan 15, 2018
Adapting the Adverse Outcome Pathway concept to biomedical research
JRC scientists have explored the application of Adverse Outcome Pathways (AOP) to improve mechanistic understanding of human disease pathophysiology in order to advance biomedical research and inform the development of new drugs.
Special issue of Toxicology in Vitro dedicated to a late JRC colleague - Dec 23, 2017
Special issue of Toxicology in Vitro dedicated to a late JRC colleague
JRC scientists have commemorated their late JRC colleague, Dr Jose-Manuel Zaldívar Comenges, by publishing a series of six papers on the Virtual Cell Based Assay a special issue of the journal Toxicology in Vitro.
Inventory of 3Rs Knowledge Sources published - Dec 22, 2017
Inventory of 3Rs Knowledge Sources published
A detailed inventory - compiled by JRC scientists - of 800 knowledge sources relevant to the Replacement, Reduction and Refinement (Three Rs) of animal procedures used for scientific purposes is now available online.
EURL ECVAM's stakeholder forum and regulatory advisors share opinions on better knowledge sharing - Dec 07, 2017
EURL ECVAM's stakeholder forum and regulatory advisors share opinions on better knowledge sharing
From the 27-29 November 2017, the annual meeting of EURL ECVAM's regulatory network (PARERE) and the joint meeting of PARERE and the ECVAM stakeholder forum (ESTAF) took place in Ispra. These meetings bring together stakeholder organisations representing academia, industry and civil society (including animal welfare NGOs) and regulators from a variety of sectors to reflect on how to progress alternative approaches to animal testing.