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Improving ways of predicting the bioconcentration of environmental chemicals in fish - Sep 19, 2018
Improving ways of predicting the bioconcentration of environmental chemicals in fish
JRC scientists have contributed to two new OECD Test Guidelines that describe how to measure in vitro fish hepatic clearance. This information is key for making more reliable predictions of bioconcentration of chemicals in fish when combined with mathematical models.
International guidance on good practice for the development and application of in vitro methods - Sep 18, 2018
International guidance on good practice for the development and application of in vitro methods
The Organisation for Economic Cooperation and Development (OECD) has published guidance on Good In Vitro Method Practices (GIVIMP) to ensure the reliability and integrity of in vitro data used for the safety assessment of chemicals. JRC scientists of the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) contributed to the guidance, within the context of a project of the OECD Test Guidelines Programme.
Improving chemical testing approaches for developmental neurotoxicity assessment - Jul 27, 2018
Improving chemical testing approaches for developmental neurotoxicity assessment
JRC scientists – in close collaboration with experts from international organisations - develop, evaluate and promote non-animal testing strategies based on in vitro methods to improve the regulatory assessment of chemicals which may cause developmental neurotoxicity (DNT) effects.
Chemical mixtures: How to address the safety of combined exposures to multiple chemicals for people and the environment - Jun 28, 2018
Chemical mixtures: How to address the safety of combined exposures to multiple chemicals for people and the environment
Every day we are exposed to low levels of hundreds of different manmade chemicals present for example in our food, consumer products and the air we breathe.
Calls for tender seek experts for training tools on alternatives to animal testing - Jun 26, 2018
Calls for tender seek experts for training tools on alternatives to animal testing
The European Commission has recently launched open calls for tender inviting experts to develop eLearning tools to facilitate uptake of non-animal alternative approaches in science.
JRC launches survey on alternatives to animal testing - Jun 04, 2018
JRC launches survey on alternatives to animal testing
The JRC launches a survey today as part of a major study aimed at providing an overview of education and training opportunities which are relevant to Replacing, Reducing or Refining the use of animals for scientific purposes – known as the '3Rs'.
EURL ECVAM renews its Scientific Advisory Committee - Jun 01, 2018
EURL ECVAM renews its Scientific Advisory Committee
New ESAC will meet in December to review affinity reagents produced using animal-free technologies and methods for skin sensitisation.
Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing - May 24, 2018
Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing
The JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a survey to collect scientific opinion on how to assess the relevance and fitness-for-purpose of complex in vitro models such as organ-on-chip devices to understand how to best facilitate their uptake and application in a variety of areas including biomedical research for drug development and toxicological testing for safety assessment.
Optimising validation studies of non-animal methods for vaccine testing - May 03, 2018
Optimising validation studies of non-animal methods for vaccine testing
New report summaries the outcome of a workshop organised by the Joint Research Centre's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) and VAC2VAC* partners on the design of multi-centre validation studies.
Reviewing the use of alternative methods in biomedical research - Apr 19, 2018
Reviewing the use of alternative methods in biomedical research
The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a study to review alternative methods and models being used for research in the areas of Respiratory Tract Diseases and Neurodegenerative Disorders.