Search results

4 items matching your search terms.
Filter the results.
Item type









New items since



Sort by relevance · date (newest first) · alphabetically
Evaluation of the neurotoxicity of chemical mixtures - Jul 13, 2012
Evaluation of the neurotoxicity of chemical mixtures
Scientists from the European Commission Joint Research Centre studied the effects of binary mixtures on neuronal networks cultured on multi-electrode array chips. The six chemicals investigated for neurotoxicity were selected according to their mode of action, the possibility for exposure of a consumer and to the amount of data available from the literature concerning their effects on the nervous system.
Located in news
Human stem cell models for neurotoxicity screening - Jun 12, 2017
Human stem cell models for neurotoxicity screening
JRC scientists have shown human induced pluripotent stem cell (hiPSC) to be a promising in vitro model for neurotoxicity testing. These stem cell-based systems offer an innovative human-relevant alternative to traditional animal tests that can improve the efficacy of drug discovery and support safety assessment.
Advancing scientific research and education with peer-reviewed video on human stem cells differentiation - Jun 26, 2017
Advancing scientific research and education with peer-reviewed video on human stem cells differentiation
JRC scientists have published a written protocol, accompanied by a video demonstration for the differentiation of human pluripotent stem cells into neurons and glia. This new tool should increase reproducibility in laboratory procedures through visual learning.
Human relevant in-vitro models for developmental neurotoxicity testing - Oct 17, 2017
Human relevant in-vitro models for developmental neurotoxicity testing
JRC scientists have shown that human induced pluripotent stem cell-derived neurons are suitable non-animal models for testing neurotoxicity during brain development. The study revealed that long term exposure to the pesticide rotenone induces oxidative stress and can trigger neuronal cell death.