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COSMOS Webinar: Automated in silico tools for in vitro to in vivo extrapolation - Apr 13, 2015
COSMOS Webinar: Automated in silico tools for in vitro to in vivo extrapolation
Information on computational tools which could be used to support chemical risk assessment
Located in news / news_docs
Computational modelling of estrogen active substances: results of a large-scale international research project - Nov 16, 2016
Computational modelling of estrogen active substances: results of a large-scale international research project
The JRC contributed to a large-scale modelling project led by the US Environmental Protection Agency (EPA) that demonstrated the usefulness of computational models in screening thousands of environmental chemicals for their ability to bind to the estrogen receptor. Chemicals that bind to the estrogen receptor may interfere with the biological effects of the natural hormone estrogen, potentially leading to adverse effects on both humans and wildlife.
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward - Dec 06, 2016 - Dec 07, 2016
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward
On 6-7th December 2016, the European Commission will hold a scientific conference in Brussels to engage the scientific community and relevant stakeholders in a debate on how to exploit cutting edge advances in biomedical and other research in the development of scientifically valid non-animal approaches (alternatives to animal testing).
JRC's EURL ECVAM publishes new Opinions from its Scientific Advisory Committee, ESAC - Dec 01, 2016
JRC's EURL ECVAM publishes new Opinions from its Scientific Advisory Committee, ESAC
The EURL ECVAM's Scientific Advisory Committee (ESAC) Opinions published by the Joint Research Centre's EURL ECVAM (the European Union Reference Laboratory for Alternatives to Animal Testing) are the outcome of the scientific peer review of five validation studies on alternative methods for skin sensitisation, skin irritation and serious eye damage/eye irritation.
JRC Summer School on Alternative Approaches for Risk assessment - THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT - May 16, 2017 - May 19, 2017
JRC Summer School on Alternative Approaches for Risk assessment  - THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT
The JRC's Chemical Safety and Alternative Methods Unit, which incorporates the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), is organising a JRC Summer School from the 16-19 May 2017, at the JRC Ispra site, on the topic of "Alternative Approaches for Risk Assessment". The overall aim is to provide comprehensive training on state-of-the-art alternative (non-animal) approaches to predictive toxicology and to promote their use within modern chemical risk assessment practice.
Call for Tender - Review of non-animal methods used in disease research
Call for Tender - Review of non-animal methods used in disease research
The JRC's EURL ECVAM has launched a study to collect and describe non-animal methods being used for basic and applied research into neurodegenerative, respiratory tract and cardiovascular diseases, and breast cancer.
Exploitation of Cell Transformation Assays for better in vitro carcinogenicity testing - Sep 18, 2017
Exploitation of Cell Transformation Assays for better in vitro carcinogenicity testing
JRC scientists – in close collaboration with the Universities of Milan and Florence in Italy – investigated the relationship between increasing concentrations of two carcinogens, namely nickel chloride and benzopyrene, and specific features of cell transformation assays (CTAs). This work paves the way for improved exploitation of CTAs for carcinogenicity testing.
Increasing momentum towards the use of alternative methods in Asia - Jul 11, 2014
Increasing momentum towards the use of alternative methods in Asia
Visit of the Korean Testing and Research Institute (KTR) to EURL ECVAM
In Vitro Methods facility - photo gallery
Located in Laboratories & Research Areas / EURL ECVAM GLP Test Facility
High Throughput Screening facility
Located in Laboratories & Research Areas / High Throughput Screening and Test Development