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Promoting the acceptance and use of chemical exposure models through transparent documentation - Nov 10, 2016
Promoting the acceptance and use of chemical exposure models through transparent documentation
JRC scientists have contributed to the development of a reporting standard for the description of chemical exposure models, in collaboration with the European Committee for Standardisation (CEN) and other stakeholders. This work was carried out within the frame of the JRC's collaboration with the CEN.
OECD publishes two Guidance Documents on integrated non-animal approaches to chemical safety assessment - Nov 10, 2016
OECD publishes two Guidance Documents on integrated non-animal approaches to chemical safety assessment
The OECD has published two Guidance Documents (GDs) on the reporting of what are termed "Defined Approaches" which are based on the integration of different kinds of non-animal data derived for example from their physicochemical properties, computational modelling or in vitro methods. Defined approaches are emerging in areas of toxicology where a combination of two or more non-animal methods is required to provide a sufficient level of information to make regulatory safety decisions about chemicals.
Computational modelling of estrogen active substances: results of a large-scale international research project - Nov 16, 2016
Computational modelling of estrogen active substances: results of a large-scale international research project
The JRC contributed to a large-scale modelling project led by the US Environmental Protection Agency (EPA) that demonstrated the usefulness of computational models in screening thousands of environmental chemicals for their ability to bind to the estrogen receptor. Chemicals that bind to the estrogen receptor may interfere with the biological effects of the natural hormone estrogen, potentially leading to adverse effects on both humans and wildlife.
JRC's EURL ECVAM publishes it latest Status Report - Nov 15, 2016
JRC's EURL ECVAM publishes it latest Status Report
The Status Report 2016 published by the Joint Research Centre's EURL ECVAM (the European Union Reference Laboratory for Alternatives to Animal Testing) provides an update on the development, validation, dissemination and regulatory acceptance of alternative approaches, building on the last status report published in September 2015.
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EURL ECVAM meets with its networks of regulators and stakeholders - Nov 21, 2016
EURL ECVAM meets with its networks of regulators and stakeholders
On the 8th of November the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) hosted a meeting of its network for the Preliminary Assessment of Regulatory Relevance (PARERE) of alternative methods, followed by a joint meeting of PARERE and the EURL ECVAM Stakeholder Forum (ESTAF).
Collaborative workshop to explore regulatory use of non-animal approaches in chemical safety assessment - Nov 21, 2016
Collaborative workshop to explore regulatory use of non-animal approaches in chemical safety assessment
On the 9-10 November the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) hosted a workshop to explore the possible regulatory use of alternative (non-animal) approaches to systemic toxicity that are intended for the hazard and safety assessment of chemicals used in a variety of sectors.
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward - Dec 06, 2016 - Dec 07, 2016
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward
On 6-7th December 2016, the European Commission will hold a scientific conference in Brussels to engage the scientific community and relevant stakeholders in a debate on how to exploit cutting edge advances in biomedical and other research in the development of scientifically valid non-animal approaches (alternatives to animal testing).
JRC's EURL ECVAM publishes new Opinions from its Scientific Advisory Committee, ESAC - Dec 01, 2016
JRC's EURL ECVAM publishes new Opinions from its Scientific Advisory Committee, ESAC
The EURL ECVAM's Scientific Advisory Committee (ESAC) Opinions published by the Joint Research Centre's EURL ECVAM (the European Union Reference Laboratory for Alternatives to Animal Testing) are the outcome of the scientific peer review of five validation studies on alternative methods for skin sensitisation, skin irritation and serious eye damage/eye irritation.
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward - Dec 13, 2016
European Commission Scientific Conference: Non-Animal Approaches - The Way Forward
On 6-7th December 2016, the European Commission held a scientific conference in Brussels to engage the scientific community and relevant stakeholders in a debate on how to exploit cutting edge advances in biomedical and other research in the development of scientifically valid non-animal approaches (alternatives to animal testing). The event was one of the four actions announced in the European Commission Communication responding to the European Citizens' Initiative "Stop Vivisection".
Review of alternatives to the use of vertebrate animals in ecotoxicity testing - Dec 13, 2016
Review of alternatives to the use of vertebrate animals in ecotoxicity testing
The JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) has contributed to a recently published overview of different approaches that are now available for ecotoxicologists and risk assessors to evaluate potentially hazardous chemicals and minimize the use of vertebrates in ecotoxicity tests.