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JRC's EURL ECVAM at the SOT 2014 53rd Annual meeting - Mar 23, 2014 - Mar 27, 2014
JRC's EURL ECVAM at the SOT 2014 53rd Annual meeting
Phoenix, Arizona - March 23-27, 2014
The pathway from liver injury to liver fibrosis - Apr 04, 2017
The pathway from liver injury to liver fibrosis
JRC scientists have used an Adverse Outcome Pathway approach to explain how some chemicals can potentially cause liver fibrosis in humans in order to support the development of non-animal approaches to chemical safety assessment.
Advancing non-animal testing methods: first set of novel knowledge tools published - Sep 30, 2016
Advancing non-animal testing methods: first set of novel knowledge tools published
The Organisation for Economic Co-operation and Development (OECD) has recently published the first five adverse outcome pathways (AOP), three of which have been developed by the JRC. The AOPs are novel knowledge management tools in toxicology and are useful for supporting risk assessment to human health. They are also valuable for helping to avoid animal testing through the use of alternative methods.
How Adverse Outcome Pathways can support computational approaches to predictive toxicology - Feb 03, 2017
How Adverse Outcome Pathways can support computational approaches to predictive toxicology
Scientists from the JRC and eleven collaborating organisations from the EU, Canada and the USA have shared their collective insights on how adverse outcome pathways (AOP) can aid the development and use of computational prediction models for regulatory toxicology.
A 21st-century roadmap for biomedical research - Feb 15, 2017
A 21st-century roadmap for biomedical research
JRC scientist contributes to the definition of a 21st-century roadmap for biomedical research which proposes the use of human-specific models and innovative in vitro technologies instead of animals.
JRC Summer School on Alternative Approaches for Risk Assessment - May 24, 2017
JRC Summer School on Alternative Approaches for Risk Assessment
From 16 to 19 May, the JRC hosted in Ispra (Italy) 101 postgraduate students and early-career scientists from 29 countries worldwide for the JRC Summer School on Alternative Approaches for Risk Assessment.
Expert workshop to capture inflammatory processes within the Adverse Outcome Pathway framework - Oct 10, 2017
Expert workshop to capture inflammatory processes within the Adverse Outcome Pathway framework
The European Commission’s Joint Research Centre (JRC) in Ispra hosted a two day workshop on 27-28th September 2017 to address how the complex and dynamic processes of inflammation could be integrated within the context of the Adverse Outcome Pathway (AOP) framework. This will contribute to the ongoing work to accelerate progress in the development of non-animal test methods.
Launch of the OECD's Adverse Outcome Pathway Knowledge Base - Sep 25, 2014
Launch of the OECD's Adverse Outcome Pathway Knowledge Base
Crowdsourcing information on toxicological mechanisms to further new animal-free approaches to chemical safety assessment
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First release of Adverse Outcome Pathway Wiki - Jul 10, 2013
First release of Adverse Outcome Pathway Wiki
A new IT tool in support of OECD's AOP Development programme enters the beta-testing phase
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