COSMOS Webinar: Automated in silico tools for in vitro to in vivo extrapolation
Apr 13, 2015
from 04:00 PM to 05:00 PM
|Contact: JRC IHCP COMMUNICATION|
|Organizer: EURL ECVAM, American Society for Cellular and Computational Toxicology (ASCCT)|
Information on computational tools which could be used to support chemical risk assessment
EURL ECVAM scientists will provide an opportunity to receive the latest information on computational tools developed by the COSMOS project within the Seurat-1 cluster. Among these computational tools, the Virtual Cell Based Assay (VCBA) and Physiologically Based Kinetic (PBK) models that are representing the fate and ADME of a chemical in a plastic well-plate and in a body, respectively. We were able to implement these mathematical models into KNIME workflows to provide automated user-friendly tools for Scientists and Risk Assessors. These automated tools can be used to extrapolate from in vitro concentration to in vivo human exposure doses or viceversa, in order to perform a chemical risk assessment. These tools are based solely on in vitro and in silico predictions thus promoting the 3Rs approaches.
This will happen via a free webinar running on the 13th of April 2015, TIME 4.00 PM CET
The webinar is hosted by the American Society for Cellular and Computational Toxicology (ASCCT), and will be of interest to risk assessors, toxicologists, modelers, and lab based scientists, to know more about computational tools as alternatives to animals testing.
This webinar took place on April 13, 2015. The presentation is available here!