JRC scientist acts as a guest editor for a special issue of 'Mutation Research' on in vitro cell transformation assays for detection of carcinogens
|Apr 13, 2012|
|Contact: JRC-IHCP, Alternatives to Animal testing|
A comprehensive picture of the development and standardisation status of CTAs (cell transformation assays) co-edited by scientist Raffaella Corvi (European Commission, Joint Research Centre).
In April 2012 a special issue on cell transformation assays was published in 'Mutation Research', drawing on knowledge gathered over 40 years of CTA use and the outcome of a recent ECVAM international validation study.
It includes details of the latest experimental protocols together with a unique photo catalogue for training end-users to obtain consistent results. Guidance is also provided on how CTAs can be best exploited in different industrial sectors for the identification of genotoxic and non-genotoxic carcinogens.
Read the special issue in 'Mutation Research/Genetic Toxicology and Environmental Mutagenesis':
International Prevalidation Study on Cell Transformation Assays, Edited by R. Corvi and Ph. Vanparys (2012) Mutation Research, vol. 744, issue 1, 1-116. Published online: http://www.sciencedirect.com/science/issue/271041-1-s2.0-S1383571812X00044