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Alternative Testing Strategies: launch of AXLR8 Progress Report 2010

News details
Dec 01, 2010

The EU-sponsored coordination action project AXLR8 (pronounced “accelerate”), aimed at finding alternatives to animal research, launched the report at the EPAA annual conference, held on 30th November 2010 in Brussels.

The AXLR8 Progress Report 2010 (see download link below) refers to new technology and approaches that provide alternatives to using animals.

Maurice Whelan, Head of Systems Toxicology Unit of the IHCP, is member of the Scientific Panel of the project.

This publication is the third in a series of reports summarising the progress of research to advance the '3Rs' concept (Replacement, Reduction and Refinement of animal tests) in Europe funded by the European Commission Directorate General for Research and Technology Development (DG-RTD) within the 'Health' theme of the Sixth and Seventh European Research Framework Programmes (FP6 and FP7, respectively) in the context of policy needs, industry requirements, and scientific challenges.


The AXLR8 Progress Report 2010 includes:


  • An introduction to the AXLR8 project

  • An update on the activities and achievements of '3Rs'-oriented research funded under the Health theme of the EU FP6 and FP7 in 2009

  • Contributions from EU member state '3Rs' centres and from colleagues who participated in the 2010 AXLR8 Scientific Workshop and public Info Forum

  • Observations by the independent AXLR8 Scientific Panel on the status of EU and international '3Rs' research and development activities

  • Suggestions for near-term research priorities to advance the science of toxicity testing, as well as EU legislative mandates in relation to the '3Rs'.


Given the substantial and increasing global investment in research aimed at developing new safety assessment methods and implementing the '3Rs' in toxicology, there is a recognized need for better information exchange and transparency in this research area. AXLR8 provides the tools for effective real-time dialogue, information exchange, problem solving, and international cooperation.


The AXLR8 Progress Report 2010 is a follow-up to the 2008 and 2009 European Commission publications, 'Alternative Testing Strategies - Replacing, reducing and refining use of animals in research' [2008 Report; 2009 Progress Report].

More info on AXLR8 web site.