JRC scientific activities in support of chemicals legislation presented to PlasticsEurope Main Food Contact Committee
|Oct 26, 2011|
|Contact: JRC-IHCP, Computational Toxicology and Modelling|
Use of JRC software Toxtree
On 20 October 2011, scientist Silvia Lapenna from the Joint Research Centre, Institute for Health and Consumer Protection (JRC-IHCP) gave an invited presentation at the PlasticsEurope Main Food Contact Committee annual meeting in Brussels.
The aim of the presentation and follow-up discussion was to introduce JRC scientific activities in support of chemicals legislation and in particular the use of the JRC software "Toxtree" in the regulatory assessment of food contact materials.
The meeting was attended by staff from twenty PlasticsEurope member companies and European Chemical Industry Council (Cefic).
PlasticsEurope is one of the leading European trade associations, producing over 90% of all polymers across the EU27 member states plus Norway, Switzerland, Croatia and Turkey.
The Toxtree software implements a variety of rulebases, including decision trees for the prediction of genotoxicity and oral systemic toxicity. These rulebases can be applied in order to estimate Thresholds of Toxicological Concern (TTC) for chemicals, especially non-intentionally added substances. Toxtree was developed by Ideaconsult Ltd (Sofia, Bulgaria) under the terms of a JRC contract. The software is made freely available as a service to scientific researchers and anyone with an interest in the application of computer-based estimation methods in the assessment of chemical toxicity.
Photo: Screenshot of Toxtree software. Copyright European Communities 2010.