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International Workshop: Low Dose Effects and Non-Monotonic Dose Responses for Endocrine Active Chemicals: Science to Practice

Event details
Sep 11, 2012 09:00 AM to
Sep 13, 2012 05:30 PM
Charité Universitätsmedizin, Berlin, Germany
Organizer: NIEHS, Pew Trust, EC JRC, Danish Ministry of the Environment, DTU, EBA, ANSES, Charité University
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This workshop seeks to lay out the evidence for low dose effects and non-monotonic dose responses in relation to endocrine active chemicals, with the goal of establishing whether the current observations are sufficient to re-examine the ways in which chemicals are tested for endocrine disrupting properties and how risk to human health may be managed.

The workshop is sponsored by

  • the National Institute of Environmental Health Sciences (NIEHS)/ NIH and the Pew Trust in the US
  • the European Commission Joint Research Centre
  • the French Agency for Food, Occupational and Environmental Health (ANSES)
  • the Federal Environment Agency (UBA) in Germany
  • the Danish Ministry of the Environment and National Food Institute from Denmark
  • Charité Medical University, Berlin.

The goals of this workshop are the following:

  • To present and discuss the state of the science for low dose effects and non-monotonic dose response curves for chemicals with endocrine activity.
  • To define research needs required to move closer to scientific agreement on low dose effects and non-monotonic dose responses for endocrine active substances.
  • To define how research programs, especially those funded by public agencies, could support studies that would produce data most useful for a science-based risk assessment.
  • To start a discussion on the implications of low dose effects and non-monotonic dose response curves to risk assessment.
  • To develop a plan to continue discussions between basic researchers and risk assessment scientists beyond the current workshop.


Who should attend

Toxicologists, environmental health scientists, regulatory agencies and risk assessors interested in all aspects of endocrine disruptors/endocrine disruption.

Meeting Organizers

  • Jerrold J. Heindel, NIEHS, USA
  • Sharon Munn, European Commission, Joint Research Centre, Institute for Health and Consumer Protection (Ispra, Italy)
  • John Bucher, NIEHS, USA
  • Thaddeus Schug, NIEHS, USA
  • Tom Zoeller, University of Massachusetts, USA
  • John Peterson Myers, Environmental Health Sciences, USA
  • Laura Vandenberg, Tufts University, USA
  • Andreas Kortenkamp, Brunell, UK
  • Andreas Gies, Wolfgang Straff, UBA, Germany
  • Gilbert Schonfelder, Charite University, Germany
  • Ulla Hass, National Food Institute, Denmark
  • Claire Beausoleil and Jean-Nicolas Ormsby, ANSES, France
  • Bernd Schaefer, BfR, Germany
  • Marie Louis Holmer, Danish Ministry of the Environment
  • Tom Neltner, Maricell Maffini, Pew Trust, USA

Scientific Contacts

Local Arrangement Contact



This workshop will not have a registration fee however all attendees must register and indicate their interest in the workshop. The workshop will be limited to 250 attendees. There will be a poster session on the first evening.

A registration form is available on the Workshop web site, to be filled-in and sent to the workshop organisers.

Poster submission

If you intend to present a poster of your work, please include your abstract on the registration form available on the workshop web site. Poster deadline is August 10. You will be notified by August 24th of the acceptance of your poster for presentation at the workshop.