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JRC-hosted EURL ECVAM confirmed as a GLP-compliant laboratory

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Jun 08, 2012
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The mandate of the EURL ECVAM is primarily to validate alternative approaches to animal testing for specific regulatory purposes, in addition to other duties laid down in the Directive 2010/63/EU on the protection of animals used for scientific purposes.

The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), hosted by the Joint Research Centre, has been inspected and confirmed as compliant with the OECD Principles of Good Laboratory Practice (GLP). The laboratory has been included in the Italian GLP compliance monitoring programme and will in the future be inspected on a regular basis.

Good laboratory practice (GLP) is a quality system concerned with the organisational process and the conditions under which non-clinical health and environmental safety studies are planned, performed, monitored, recorded, archived and reported. It aims to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of non-clinical safety tests for chemicals (including pharmaceuticals) - from physio-chemical properties to kinetic and dynamic toxicity.

Comparable quality of test data for chemical safety assessments forms the basis of the OECD Council decision from 1981 on the Mutual Acceptance of Data (MAD). If individual countries can confidently rely on test data developed in other countries, duplicative testing can be avoided, thereby saving time, resources and animals used for testing. By applying MAD, GLP principles and data generated in accordance with OECD Test Guidelines, trade barriers can be avoided, and the protection of human health and the environment further improved.