On April 27, 2009, representatives from four international agencies signed a Memorandum of Cooperation (MOC) establishing an International Cooperation on Alternative Test Methods (ICATM).

These 4 agencies are:

  • for Japan: Japanese Center for the Validation of Alternative Methods (JaCVAM)
  • for the U.S.: National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), a component of the National Institute of Environmental Health Sciences, administering the U.S. Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM);
  • for E.U.: ECVAM (the European Center for Validation of Alternative Methods)
  • for Canada: Environmental Health Science and Research Bureau within Health Canada.

The agreement promotes enhanced international cooperation and coordination on the scientific validation of non- and reduced-animal toxicity testing methods.

On March 8, 2011, following signature of an agreement, ICATM expanded to include a fifth member, KoCVAM (the Republic of Korea's Centre for the Validation of Alternative Methods).




ICATM Memorandum of Cooperation

W. Stokes,pdf icon ICATM Overview (March 2011)

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