Public Comments

EURL ECVAM summarises its final appraisal of the performance, applicability, limitations and proper scientific use of test methods in its "EURL ECVAM recommendations". Before finalising and publishing these recommendations, EURL ECVAM, as a matter of routine, invites comments from the general public.

Below you will find a list of open as well as closed and archived public commenting rounds concerning test methods that have undergone evaluation, validation, peer review and final appraisal by EURL ECVAM.

Open commenting rounds

Date

Request for comments

30.03.2017-

16.04.2017

Invitation of public comments on the draft EURL ECVAM Recommendation on the use of non-animal approaches for skin sensitisation testing


 

Archive of commenting rounds

 

DateRequest for comments
Final text

28.11.2014 - 31.12.2014

 

24.05.2014 - 30.06.2014  

Invitation of public comments on the draft EURL ECVAM Recommendation on the human Cell Line Activation Test (h-CLAT) for skin sensitisation testing

 

Invitation of public comments on the draft EURL ECVAM recommendation concerning the Zebrafish Embryo Acute Toxicity Test Method (ZFET)

EURL ECVAM Recommendation

 

EURL ECVAM Recommendation

13.11.2013 – 29.11.2013  Invitation of public comments on the draft EURL ECVAM recommendation concerning the KeratinosensTM assay for skin sensitisation testing. Details available pdf icon here  EURL ECVAM Recommendation
01.08.2013 – 13.09.2013

Invitation of public comments on the draft EURL ECVAM recommendation on the Direct Peptide Reactivity Assay (DPRA) for skin sensitisation testing

EURL ECVAM Recommendation
01.08.2013 – 13.09.2013

Invitation of public comments on the draft EURL ECVAM recommendation on the BHAS Cell Transformation Assay (BHAS CTA) for carcinogenicity testing

EURL ECVAM Recommendation
09.12.2011 - 31.12.2011 Public comments on draft ECVAM recommendation on the Cell Transformation Assays using Syrian Hamster Embryo Cells (SHE) and the BALB/c 3T3 mouse fibroblast cell line for in vitro carcinogenicity testing. Details available here  ECVAM Recommendation
20.12.2012 - 31.01.2013 Public comments on draft EURL ECVAM recommendation concerning the 3T3 Neutral Red Uptake cytotoxicity test method. The assay was recently validated by EURL ECVAM for its possible use to support the identification of substances not requiring classification for acute oral toxicity. Details available here  ECVAM Recommendation

 

 Contact:  JRC-ECVAM-CONTACT@ec.europa.eu 

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highlights

Regulators adopt mechanistically-based non-animal test methods to assess the potential of chemicals to cause skin allergy Regulators adopt mechanistically-based non-animal test methods to assess the potential of chemicals to cause skin allergy - Apr 26, 2016 EURL ECVAM validated methods adopted by the OECD paved the way for the revision of regulatory requirements for skin sensitisation under REACH