EURL ECVAM engagement with regulators and stakeholders – early and often
|Sep 27, 2012|
|Contact: JRC-IHCP, Alternatives to Animal Testing|
This was the key message delivered by the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) at the meeting it hosted over the past two days (25-26 Sept) involving both its regulatory advisory network (PARERE) and stakeholder forum (ESTAF).
Issues that were tackled included how to design Integrated Testing Strategies (ITS) based on understanding toxicological mode-of-action, what factors determine the regulatory relevance of alternative methods, and how best to gain acceptance by decision makers.
EURL ECVAM also used the occasion to present its new strategy for achieving the full replacement of animal testing for identification of skin sensitisation hazard. Achieving this aim in the coming years will result in the saving of thousands of animals, particularly in relation to classification of chemicals and satisfying information requirements under REACH. Progress will also help in predicting the potency of a sensitiser, central to the safety assessment of cosmetic ingredients.
The strategy was well received and the feedback provided by the participants will be incorporated into a final version to be released in the coming weeks. A number of PARERE and ESTAF members including industrial associations, NGOs and regulatory agencies expressed their willingness to actively contribute to its implementation and to cooperate with ECVAM in achieving its goals.
Photo: Meeting of PARERE and ESTAF on 26 September 2012 at the JRC, Ispra. Copyright EU 2012.