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Three Rs Approaches in the Production and Quality Control of Avian Vaccines. ECVAM Workshop Report 41. Bruckner, L. et al. (2000) ATLA 28, 241-258.

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Jul 10, 2000
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Bruckner, L. et al.

Bruckner, L. et al. (2000) ATLA 28, 241-258.

 

The joint ECVAM/AGAATI (Advisory Group on Alternatives to Animal Testing in Immunobiologicals) workshop on 'Three Rs Approaches in the Production and Quality Control of Avian Vaccines' was held in Langen, Germany, on 11–13 June 1999, under the co-chairmanship of Lukas Bruckner (Institute of Virology and Immunoprophylaxis, Mittelhäusern, Switzerland) and Guy Zigterman (Intervet, Boxmeer, The Netherlands). The participants, all experts in vaccine quality control, avian vaccines or avian diseases, came from international regulatory or government organisations, national control laboratories, vaccine manufacturers and academia. The objectives of the workshop were:
a) to review the monographs of the
European Pharmacopoeia on avian live viral vaccines in the light of animal welfare aspects;

b) to propose and recommend strategies to replace, reduce and/or refine the use of animals;

c) to review the state-of-the-art and the suitability of the tests proposed for their intended purposes; and

d) to comment on the draft monographs on avian live viral vaccines which had been published in Pharmeuropa (2–12). The outcome of the discussions and the recommendations agreed by the workshop participants are summarised in this report.