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Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testingdefault frame updated video

Transcripts: pdf icon EN; FR; DE; IT.

1 October 2018


EURL ECVAM will launch a new website from 1 October on the EU Science Hub (https://ec.europa.eu/jrc/en).
Please, update your bookmarks accordingly!


 The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre. As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

Improving ways of predicting the bioconcentration of environmental chemicals in fish Improving ways of predicting the bioconcentration of environmental chemicals in fish - Sep 19, 2018 JRC scientists have contributed to two new OECD Test Guidelines that describe how to measure in vitro fish hepatic clearance. This information is key for making more reliable predictions of bioconcentration of chemicals in fish when combined with mathematical models.
International guidance on good practice for the development and application of in vitro methods International guidance on good practice for the development and application of in vitro methods - Sep 18, 2018 The Organisation for Economic Cooperation and Development (OECD) has published guidance on Good In Vitro Method Practices (GIVIMP) to ensure the reliability and integrity of in vitro data used for the safety assessment of chemicals. JRC scientists of the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) contributed to the guidance, within the context of a project of the OECD Test Guidelines Programme.
Improving chemical testing approaches for developmental neurotoxicity assessment Improving chemical testing approaches for developmental neurotoxicity assessment - Jul 27, 2018 JRC scientists – in close collaboration with experts from international organisations - develop, evaluate and promote non-animal testing strategies based on in vitro methods to improve the regulatory assessment of chemicals which may cause developmental neurotoxicity (DNT) effects.
Chemical mixtures: How to address the safety of combined exposures to multiple chemicals for people and the environment Chemical mixtures: How to address the safety of combined exposures to multiple chemicals for people and the environment - Jun 28, 2018 Every day we are exposed to low levels of hundreds of different manmade chemicals present for example in our food, consumer products and the air we breathe.
Calls for tender seek experts for training tools on alternatives to animal testing Calls for tender seek experts for training tools on alternatives to animal testing - Jun 26, 2018 The European Commission has recently launched open calls for tender inviting experts to develop eLearning tools to facilitate uptake of non-animal alternative approaches in science.
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calls

Horizon 2020 Call on new testing and screening methods to identify endocrine disrupting chemicals Horizon 2020 Call on new testing and screening methods to identify endocrine disrupting chemicals JRC collaboration with successful consortia responding to the H2020 SC1-BHC-27-2018 Call on "New testing and screening methods to identify endocrine disrupting chemicals"
Call for Tender - Review of non-animal methods used in disease research Call for Tender - Review of non-animal methods used in disease research The JRC's EURL ECVAM has launched a study to collect and describe non-animal methods being used for basic and applied research into neurodegenerative, respiratory tract and cardiovascular diseases, and breast cancer.
Call for experts to serve on EURL ECVAM's Scientific Advisory Committee (ESAC) Call for experts to serve on EURL ECVAM's Scientific Advisory Committee (ESAC) The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is renewing membership of its EURL ECVAM Scientific Advisory Committee (ESAC). Interested scientific experts who satisfy the eligibility criteria and who possess the relevant competences are invited to apply (Deadline 31st January 2017).
EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) Supporting the validation and implementation of in vitro methods for regulatory use
Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
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multimedia

Toxicological Testing of Chemicals & EURL ECVAM Toxicological Testing of Chemicals & EURL ECVAM Faces of Science - showcasing the human face of the scientific advice supporting EU policy. Maurice Whelan at the Joint Research Centre, the European Commission's in-house science service, presents the Toxicological Testing of Chemicals and EURL ECVAM
New EURL ECVAM video explains the validation process of alternative methods (in Italian) New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods