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The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP) located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP). As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

Alternatives to animal testing - EU Public survey launched Alternatives to animal testing - EU Public survey launched - Feb 01, 2016 Accelerating progress in the Replacement, Reduction and Refinement of animal testing through better knowledge sharing
The 3Rs in the quality control of human vaccines: EURL ECVAM releases summary of ongoing projects The 3Rs in the quality control of human vaccines: EURL ECVAM releases summary of ongoing projects - Jan 20, 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre has just released its report summarising ongoing projects to replace, reduce and refine the use of animals in the quality control of human vaccines.
Assessing performance of new or improved genotoxicity tests: EURL ECVAM publishes an updated recommended list of reference chemicals Assessing performance of new or improved genotoxicity tests: EURL ECVAM publishes an updated recommended list of reference chemicals - Dec 21, 2015 Reference chemical selection is a key step in the development, optimisation and validation of alternative test methods. In light of newly available data, the JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), supported by a group of experts, has revised its recommended list of genotoxic and non-genotoxic chemicals for assessing the performance of new or improved in vitro genotoxicity test methods.
A global approach towards alternatives to animal testing: Meeting of the International Cooperation of Alternative Test Methods (ICATM) 10-11 November 2015, JRC, Ispra A global approach towards alternatives to animal testing: Meeting of the International Cooperation of Alternative Test Methods (ICATM) 10-11 November 2015, JRC, Ispra - Nov 17, 2015 Members of the International Cooperation on Alternative Test Methods attended a two-day meeting hosted by the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM). Representatives from organisations involved in method validation discussed a variety of topics including; on-going cooperation in validation studies; activities at the OECD concerning test guideline development; the differences in toxicological hazard information requirements across sectors and jurisdictions; and how to better engage the international regulatory community towards better understanding and acceptance of alternative methods
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calls

EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) Supporting the validation and implementation of in vitro methods for regulatory use
Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
Call for expressions of interest - EURL ECVAM Stakeholder forum (ESTAF) Open Invitation addressed to stakeholder organisations
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multimedia

Toxicological Testing of Chemicals & EURL ECVAM Toxicological Testing of Chemicals & EURL ECVAM Faces of Science - showcasing the human face of the scientific advice supporting EU policy. Maurice Whelan at the Joint Research Centre, the European Commission's in-house science service, presents the Toxicological Testing of Chemicals and EURL ECVAM
New EURL ECVAM video explains the validation process of alternative methods (in Italian) New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods