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March 5th, 2015: Fifth of 6 free REACH seminars with contributions of EURL ECVAM scientists: "Alternative approaches to mammalian acute systemic toxicity testing" Read more...
Updated information on alternative methods and testing strategies that could be used to meet REACH requirements

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Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testingdefault frame updated video

Transcripts: pdf icon EN; FR; DE; IT.

The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP) located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre, Institute for Health and Consumer Protection (IHCP). As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

Reducing animal testing for skin allergies Reducing animal testing for skin allergies - Mar 02, 2015 The JRC has validated and recommended a new method, not based on animal testing, which identifies chemicals that can trigger skin allergies, estimated to affect already 20% of the population in Europe.
Breakthrough towards animal-free testing for chemicals that might cause skin allergies Breakthrough towards animal-free testing for chemicals that might cause skin allergies - Feb 05, 2015 Today's adoption by the OECD of two new test guidelines will contribute to reducing the number of animals currently used worldwide to identify chemicals with the potential to trigger skin allergies.
Alternative approaches for acute systemic toxicity testing: EURL ECVAM releases its strategy Alternative approaches for acute systemic toxicity testing: EURL ECVAM releases its strategy - Dec 19, 2014 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre has just released a strategy on how to replace, reduce and refine the use of animals for acute mammalian systemic toxicity testing
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events

Alternative approaches to mammalian acute systemic toxicity testing - Fifth free REACH seminar (one of six) Alternative approaches to mammalian acute systemic toxicity testing - Fifth free REACH seminar (one of six) - Mar 05, 2015 Updated information on alternative methods and testing strategies that could be used to meet REACH information requirements on aspects of toxicological hazard of registered chemicals
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calls

Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
Call for expressions of interest - EURL ECVAM Stakeholder forum (ESTAF) Open Invitation addressed to stakeholder organisations