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Our scientists show you what they are doing to advance safety assessment of chemicals without relying on animal testingdefault frame updated video

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EURL ECVAM will launch a new website on the EU Science Hub (https://ec.europa.eu/jrc/en).
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The European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has been formally established in 2011, due to the increasing need for new methods to be developed and proposed for validation in the European Union. EURL ECVAM is hosted by the Joint Research Centre located in Ispra, Italy.

EURL ECVAM has a long tradition in the validation of methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines. Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.

EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

The European Commission's involvement in activities targeted to the validation of alternative approaches to animal testing started in 1991, with the launch of ECVAM (the European Centre for the Validation of Alternative Methods), hosted by the Joint Research Centre. As from 2011, ECVAM's tasks are assigned to EURL ECVAM.Cell culture under sterile conditions-2

The menu on the left hand side of the page helps you browse through the main content sections of the EURL ECVAM web site.

To contact EURL ECVAM, please use this interactive form.

Photo: Cell culture under sterile conditions in the EURL ECVAM microbiology laboratory. Copyright EU 2012.

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highlights

JRC launches survey on alternatives to animal testing JRC launches survey on alternatives to animal testing - Jun 04, 2018 The JRC launches a survey today as part of a major study aimed at providing an overview of education and training opportunities which are relevant to Replacing, Reducing or Refining the use of animals for scientific purposes – known as the '3Rs'.
EURL ECVAM renews its Scientific Advisory Committee EURL ECVAM renews its Scientific Advisory Committee - Jun 01, 2018 New ESAC will meet in December to review affinity reagents produced using animal-free technologies and methods for skin sensitisation.
Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing Survey on issues influencing end-user confidence in complex in vitro models for use in research and testing - May 24, 2018 The JRC's European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a survey to collect scientific opinion on how to assess the relevance and fitness-for-purpose of complex in vitro models such as organ-on-chip devices to understand how to best facilitate their uptake and application in a variety of areas including biomedical research for drug development and toxicological testing for safety assessment.
Optimising validation studies of non-animal methods for vaccine testing Optimising validation studies of non-animal methods for vaccine testing - May 03, 2018 New report summaries the outcome of a workshop organised by the Joint Research Centre's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) and VAC2VAC* partners on the design of multi-centre validation studies.
Reviewing the use of alternative methods in biomedical research Reviewing the use of alternative methods in biomedical research - Apr 19, 2018 The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a study to review alternative methods and models being used for research in the areas of Respiratory Tract Diseases and Neurodegenerative Disorders.
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calls

Horizon 2020 Call on new testing and screening methods to identify endocrine disrupting chemicals Horizon 2020 Call on new testing and screening methods to identify endocrine disrupting chemicals JRC collaboration with successful consortia responding to the H2020 SC1-BHC-27-2018 Call on "New testing and screening methods to identify endocrine disrupting chemicals"
Call for Tender - Review of non-animal methods used in disease research Call for Tender - Review of non-animal methods used in disease research The JRC's EURL ECVAM has launched a study to collect and describe non-animal methods being used for basic and applied research into neurodegenerative, respiratory tract and cardiovascular diseases, and breast cancer.
Call for experts to serve on EURL ECVAM's Scientific Advisory Committee (ESAC) Call for experts to serve on EURL ECVAM's Scientific Advisory Committee (ESAC) The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is renewing membership of its EURL ECVAM Scientific Advisory Committee (ESAC). Interested scientific experts who satisfy the eligibility criteria and who possess the relevant competences are invited to apply (Deadline 31st January 2017).
EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) EURL ECVAM extends the EU Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL) Supporting the validation and implementation of in vitro methods for regulatory use
Horizon 2020 Call on New approaches to improve predictive human safety testing Horizon 2020 Call on New approaches to improve predictive human safety testing The role of JRC / EURL ECVAM in cooperating with successful consortia
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multimedia

Toxicological Testing of Chemicals & EURL ECVAM Toxicological Testing of Chemicals & EURL ECVAM Faces of Science - showcasing the human face of the scientific advice supporting EU policy. Maurice Whelan at the Joint Research Centre, the European Commission's in-house science service, presents the Toxicological Testing of Chemicals and EURL ECVAM
New EURL ECVAM video explains the validation process of alternative methods (in Italian) New EURL ECVAM video explains the validation process of alternative methods (in Italian) This video presents the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and explains the validation process of alternative methods